Jun 30, 2015
Dr Lena Palaniyappan qualified as a medical doctor from Stanley Medical College, Chennai, India along with a concurrent BA in Psychology. Since 2004 he has trained as a clinical psychiatrist, initially at the Maudsley Hospital, London and later at Nottingham where he obtained his M.Med.Sci. in Clinical Psychiatry. Between 2007 and 2009 he worked as an Academic Clinical Fellow (NIHR funded) at the Regional Affective Disorders Unit at Newcastle-upon-Tyne. Following a HEFCE funded clinical lecturer post during which he coordinated a MRC funded neuroimaging study in psychosis led by Prof. Liddle, he obtained a Wellcome Trust funded Clinical Research Fellowship in Translational Neuroimaging in Psychiatry.
He recently assumed the role of Associate Director of the Centre for Translational Neuroimaging in Mental Health. He is also a member of the editorial board for Frontiers in Neuropsychiatric Imaging and Stimulation. As a consultant psychiatrist, he works with young people who experience a psychotic episode for the first time in their lives.
My present clinical research aims to apply brain imaging to investigate symptom burden, treatment response and prognostic accuracy in major psychiatric disorders such as schizophrenia, bipolar disorder and depression.
To this end, my work focuses on understanding the intrinsically organized, large-scale brain networks in psychosis using structural, functional and electrophysiological imaging techniques. I am interested in the clinical application of neuroimaging observations made at an individual level (rather than group level) using advanced statistical approaches and mathematical models. I am also interested in developing hypothesis-driven neuromodulatory approaches that target resistant symptoms of depression and psychosis through the manipulation of dysfunctional brain networks (e.g. using magnetic stimulation and cognitive training approaches).
The major goal of my work is to understand the pathways that lead to poor long-term outcome in certain individuals with serious mental disorders.
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